Wollastonite exposure and lung fibrosis.
نویسندگان
چکیده
Wollastonite is a naturally occurring acicular or fibrous metasilicate used in ceramics and as a substitute for asbestos in some applications. Wollastonite fibers are rather similar in form, length, and diameter to amphibole asbestos fibers but mineralogically they are different. Dust measurements in both the Finnish limestone--wollastonite quarry and in the flotation plant yielded high concentrations of both total dust and respirable fibers in some operational stages. The clinical study comprised a total of 46 men who had been exposed to wollastonite at the quarry for at least 10 years. Three of the fifteen nonsmokers showed chronic bronchitis. Radiographs revealed slight lung fibrosis among fourteen men, and slight bilateral pleural thickening among thirteen men. Their sputum specimens were normal. Spirometry and nitrogen single breath tests indicated the possibility of small airways disease.
منابع مشابه
Occupational and Environmental Medicine 1995;52:621-624 Fibrogenic effect of woliastonite compared with asbestos dust and dusts
a day, 5 days a week for 12 months plus 12 months observation, or for a full 24 months) inhalation exposure of wollastonite in rats (McConnell et al, 1991), I was surprised to find the authors of this article reporting pulmonary fibrosis after intratracheal (IT) instillation. I offer the following comments and possible explanation for this unexpected result. It is difficult to determine from th...
متن کاملOccupational and Environmental Medicine 1995;52:621-624 Fibrogenic effect of woliastonite compared with asbestos dust and dusts
a day, 5 days a week for 12 months plus 12 months observation, or for a full 24 months) inhalation exposure of wollastonite in rats (McConnell et al, 1991), I was surprised to find the authors of this article reporting pulmonary fibrosis after intratracheal (IT) instillation. I offer the following comments and possible explanation for this unexpected result. It is difficult to determine from th...
متن کاملRespiratory morbidity in wollastonite workers.
Medical and environmental surveys were conducted at a wollastonite mine and mill in 1976 and in 1982. Health testing included chest radiography, spirometry, and a questionnaire. Workers at a nearby electronics plant were also examined in 1982 for a comparison of lung function and respiratory symptoms. Both wollastonite and control workers showed significant smoking effects for chronic respirato...
متن کاملHuman epidemiology: a review of fiber type and characteristics in the development of malignant and nonmalignant disease.
Consideration of the human epidemiology of diseases arising from exposure to naturally occurring and man-made mineral fibers encompasses the several forms of asbestos (chrysotile, crocidolite, amosite, anthophyllite, tremolite-actinolite), other naturally occurring silicates (talc, sepiolite, erionite, attapulgite, vermiculite, and wollastonite), and man-made mineral fibers (glass continuous fi...
متن کاملBiopersistence of inhaled organic and inorganic fibers in the lungs of rats.
Fiber dimension and durability are recognized as important features in influencing the development of pulmonary carcinogenic and fibrogenic effects. Using a short-term inhalation bioassay, we have studied pulmonary deposition and clearance patterns and evaluated and compared the pulmonary toxicity of two previously tested reference materials, an inhaled organic fiber, Kevlar para-aramid fibrils...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Environmental research
دوره 30 2 شماره
صفحات -
تاریخ انتشار 1983